Zuckerberg SF General: The Hospital at Potrero and 23rd

Most people drive past ZSFG on the 101 and don’t think much about it. Getting a vaccine here puts you on the ground floor.

Zuckerberg San Francisco General Hospital exterior with large metallic ring sculpture in front and sun flare above the brick building

The original building is 1915 brick. The newer addition wraps around it with white concrete and floor-to-ceiling glass. There’s a large steel ring sculpture out front — hard to miss.

Zuckerberg San Francisco General Hospital and Trauma Center building sign on the modern glass facade

It was renamed from SF General in 2015 when Mark Zuckerberg and Priscilla Chan donated $75 million. The naming was controversial — a public hospital named after a tech billionaire. The mission didn’t change: still the city’s only Level 1 trauma center. Still the main safety-net hospital for uninsured patients and Medi-Cal.

During the COVID rollout it became one of SF’s major vaccination sites. The SFHN operation was running smoothly when I got my first Pfizer shot here in April 2021.

Potrero and 23rd. Muni 10-Townsend stops nearby.